The FDA (Food and Drug Administration) does not regulate manufacturing of sex toys or the materials used to do so.
Many sex toys and most condoms are made of Latex or PVC and often also contain phthalates which is added to keep latex soft and pliable. Contact with latex causes sensitivity over time due to a cumulative affect with each use. Often people are initially allergic to latex and suffer severe symptoms when in contact with it.
The symptoms of latex allergy may be relatively mild, but can include burning or stinging and itching, urinary tract and/or bladder infection, high fever, liver and/or kidney damage and death. Even though you may not be allergic to latex at first- it will build up in your body and with continued exposure most people will eventually have a reaction to it.
The additive phthalate is also toxic, as is PVC (polyvinyl chloride). Both are known carcinogens. But phthalates are EXTREMELY DANGEROUS causing changes in the endocrine system, changes in hormone levels, birth defects, breast cancer and more. Please read THIS ARTICLE for more about phthalates.
The good news is- silicone and rubber are safe. So as long as you purchase 100% silicone or 100% rubber sex toys you can play safely.
However- a manufacturer can label a sex toy as made of silicone or rubber as long as silicone or rubber is the MAIN ingredient, and many times even though a sex toy may say it is silicone, it may not be 100% silicone and can contain latex , phthalates or pvc. When you purchase a sex toy it is very important to make certain that it is made of 100% silicone or rubber.